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A novel anti-metastatic extract from Stellera chamaejasme Linn.suppresses breast tumor cell motility through inhibition of focal adhesion kinase

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摘要 To the Editor:In breast cancer,it is the metastasis that makes a clear distinction between life and death.^([1,2])However,effective treatment targeted against metastasis remains an unmet clinical need.^([2,3])Accumulating evidence suggests that an essential step in metastasis is tumor cell acquisition of motility.^([2])Furthermore,epithelial-mesenchymal transition(EMT)initiates the early steps of tumor cell spread by endowing them with greater motility and invasiveness.
出处 《Chinese Medical Journal》 SCIE CAS CSCD 2022年第24期3004-3006,共3页 中华医学杂志(英文版)
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