Application of computer-aided diagnosis of congenital heart disease in four-chamber view of fetal heart basic screening

To the Editor:Congenital heart disease(CHD)is the most common severe congenital malformation which threatens the health of the fetus and the primary factor of intrauterine death.Prenatal detection of severe CHD could reduce the neonatal mortality and morbidity.The detection rate ranges between 25.0%and 59.7%in the prenatal ultrasonographic examination.^([1])We need to identify new strategies to improve detection rates of CHD prenatally.Deep-learning(DL)-based computer-aided diagnosis(CAD)has been highly and rapidly developed in recent years.