不明原因反复胚胎种植失败和不明原因反复自然流产的临床治疗策略比较

Comparison of clinical therapeutic strategy between unexplained recurrent implantation failure and unexplained recurrent spontaneous abortion

胚胎种植失败和流产均属于妊娠丢失的范畴,但它们发生在不同的生理阶段。部分患者出现反复胚胎种植失败(RIF)或反复自然流产(RSA),常规检查未能发现明确病因,临床上难以对这些情况进行针对性的诊治,经验性用药往往缺乏循证医学依据。本文就不明原因反复胚胎种植失败(URIF)和不明原因反复自然流产(URSA)两者的诊断及不同临床治疗策略之间疗效的区别等内容展开综述。

Both implantation failure and miscarriage belong to the category of pregnancy loss,but they occur at in different physiological stages.Some patients suffered from recurrent implantation failure(RIF)or recurrent spontaneous abortion(RSA),while there was no obvious cause could be found in routine examinations.Thus,targeted therapy is difficult and empirical medication often lacks of evidence-based support.This paper reviews the differences in diagnosis of unexplained recurrent embryo implantation failure(URIF)and unexplained recurrent spontaneous abortion(URSA)and their clinical treatment strategies.