早产儿PICC相关胸腔积液胸水实验室检查分析

目的探讨早产儿外周置入中心静脉导管(PICC)相关胸腔积液的胸水检查特点。方法选取2011年6月至2021年12月本院新生儿重症监护室行PICC并发生胸腔积液的早产儿病例进行回顾性分析,总结临床资料及胸水实验室检查的特点。结果共有1,115例早产儿成功行PICC置管,12例在使用期间发生胸腔积液,其中11例行胸腔穿刺治疗,胸水均在48 h内吸收,胸水检查示一例因有损伤呈红色浑浊液,其余均呈白色或黄色浑浊液,李凡他实验阳性,细胞数(42~760)×10^(6)/L,葡萄糖定量(6.4~20.6)mmol/L,蛋白定量(8.8~50.8)g/L。结论PICC相关胸腔积液经过积极胸腔穿刺治疗临床预后好,胸水检查提示细胞数小于1,000×10^(6)/L,葡萄糖定量远高于正常血糖水平。

Objective To analyze the results of chest water laboratory examination of peripherally inserted central catheters(PICC)-associated pleural effusion in preterm infants,and to summarize the characteristics of pleural effusion in preterm infants with PICC.Methods The clinical data and the results of chest water examination were analyzed by collecting the cases of pleural effusion in preterm infants with PICC from June 2011 to December 2021 in the neonatal intensive care unit of our hospital.Results A total of 1115 preterm infants were successfully retained PICC,of which 12 cases developed pleural effusion(PLE)during use.11 of which underwent pleural puncture treatment,and pleural effusion was absorbed within 48 hours.The pleural effusion examination showed that one patient was red turbid fluid due to injury,and the rest were white or yellow turbid fluid.Lifant's test was positive,the cell number was(42~760)×10^(6)/L,which was less than 1000×10^(6)/L,the glucose quantitative was(6.40~20.64)mmol/L,and the protein quantitative was(8.7~50.77)g/L.Conclusion Positive pleural puncture treatment for PICC-associated pleural effusion has a good clinical prognosis.Pleural effusion examination showes that the cell number is less than 1000×10^(6)/L,and the glucose level is much higher than the normal blood glucose level.