腹腔镜与开腹胃癌根治术治疗早期胃癌的效果观察

Effect observation of laparoscopic and open radical gastrectomy in the treatment of early-stage gastric cancer

目的对比腹腔镜与开腹胃癌根治术治疗早期胃癌的临床效果。方法80例早期胃癌患者,根据数字盲选法分为对照组和观察组,各40例。对照组行开腹胃癌根治术治疗,观察组行腹腔镜胃癌根治术治疗。比较两组患者术后并发症发生情况、围术期相关指标(术中出血量、切口长度、首次肛门排气时间、首次下床活动时间、首次进食时间、术后住院时间及淋巴结清除数)及视觉模拟评分法(VAS)评分。结果观察组术后并发症发生率5.00%低于对照组的22.50%,差异有统计学意义(P<0.05)。两组淋巴结清除数比较,差异无统计学意义(P>0.05);观察组术中出血量(165.50±23.50)ml少于对照组的(360.50±50.20)ml,切口长度(2.50±1.20)cm、首次肛门排气时间(1.50±0.50)h、首次下床活动时间(2.50±0.50)d、首次进食时间(4.30±0.50)d、术后住院时间(11.50±2.50)d均短于对照组的(14.30±1.50)cm、(3.20±0.50)h、(4.50±0.80)d、(6.50±0.50)d、(14.30±2.50)d,VAS评分(2.30±0.50)分低于对照组的(4.50±0.80)分,差异有统计学意义(P<0.05)。结论与开腹胃癌根治术比较,腹腔镜胃癌根治术更适用于早期胃癌治疗中,具有微创、恢复快等优势。

Objective To compare the clinical effect of laparoscopic and open radical gastrectomy in the treatment of early-stage gastric cancer.Methods A total of 80 patients with early-stage gastric cancer were divided into a control group and an observation group according to the numerical blind selection method,with 40 cases in each group.The control group was treated with open radical gastrectomy,and the observation group was treated with laparoscopic radical gastrectomy.Both groups were compared in terms of occurrence of postoperative complications,perioperative related indexes(intraoperative blood loss,incision length,first anal exhaust time,first off-bed activity time,time to first food intake,postoperative hospital stay and number of lymph nodes dissection)and visual analogue scale(VAS)score.Results The incidence of postoperative complications in the observation group was 5.00%,which was lower than that of 22.50%in the control group,and the difference was statistically significant(P<0.05).The difference was not statistically significant when comparing the number of lymph node dissection between the two groups(P>0.05).The amount of intraoperative blood loss in the observation group was(165.50±23.50)ml,which was less than that of(360.50±50.20)ml in the control group;the observation group had incision length of(2.50±1.20)cm,first anal exhaust time of(1.50±0.50)h,first off-bed activity time of(2.50±0.50)d,time to first food intake(4.30±0.50)d,and postoperative hospital stay(11.50±2.50)d were shorter than those of(14.30±1.50)cm,(3.20±0.50)h,(4.50±0.80)d,(6.50±0.50)d,and(14.30±2.50)d in the control group;the VAS score in the observation group was(2.30±0.50)points,which was lower than that of(4.50±0.80)points in the control group;the differences were statistically significant(P<0.05).Conclusion Compared with open radical gastrectomy,laparoscopic radical gastrectomy is more suitable for the treatment of early-stage gastric cancer,and has the advantages of minimally invasive and quick recovery.