摘要
clinical trials of solid tumours is mainly due to their highly immunosuppressive tumour microenvironment(TME).1 Regulatory T cells(Tregs),a subset of T cells that control the autoimmune response and are one of the main components of immunosuppressive TME,can regulate the immune response intensity and inhibit the function and activity of effector T cells,thus inducing immune tolerance and maintaining immune response homeostasis.In solid TME,Tregs mediate the immune escape of tumour cells by inhibiting the body’s immune response,affecting the efficacy of prognosis.
