碘甘油联合盐酸米诺环素治疗牙周炎的临床效果及对患者睡眠质量的影响

Effect of Iodine Glycerin Combined with Minocycline Hydrochloride on Periodontitis and Sleep Quality of Patients

目的:研究碘甘油联合盐酸米诺环素治疗牙周炎的临床效果以及对睡眠质量的影响。方法:选取2021年1月至2022年10月晋江市安海镇卫生院收治的牙周炎患者60例作为研究对象,按照随机数字表法随机分为对照组和观察组,每组30例。观察组采用碘甘油结合盐酸米诺环素治疗,对照组仅使用碘甘油治疗,比较2种治疗方法对牙周指标、疼痛程度和睡眠质量的影响。结果:治疗后,2组患者牙周相关指标(牙周探诊深度、龈沟出血指数、菌斑指数、附着水平)均有显著改善,且观察组的改善幅度均大于对照组,2组比较差异有统计学意义(P<0.05);治疗后,观察组患者的疼痛评分小于对照组,2组比较差异有统计学意义;治疗后,2组患者PSQI评分均降低,且观察组的总PSQI评分小于对照组,2组比较差异有统计学意义(P<0.05)。结论:采用碘甘油结合盐酸米诺环素治疗牙周炎的临床优势显著,更有利于减轻疼痛程度,改善牙周指标,同时有利于改善患者的睡眠质量,值得临床推广应用。

Objective:To study the effect of iodine glycerin combined with minocycline hydrochloride in the treatment of periodontitis and the influence of this treatment on sleep quality.Methods:A total of 60 patients with periodontitis admitted to Anhai Town Hospital From January 2021 to October 2022 were enrolled as the research object,and they were divided into 30 patients/group according to the principle of random number table.The observation group was treated with iodine glycerin combined with minocycline hydrochloride,while the control group was only treated with iodine glycerin.The effects of the two treatment methods on periodontal indicators,pain degree and sleep quality were compared.Results:Periodontal indexes:The periodontal related indexes(periodontal probing depth,gingival sulcus bleeding index,plaque index,attachment level)of the observation group and control group after treatment were significantly improved compared with those before treatment,and the improvement range of the observation group was greater than that of the control group,with statistical significance(P<0.05);Pain degree:the pain score of patients in the observation group after treatment was lower than that before treatment and in the control group,with statistical significance(P<0.05);Sleep quality:after treatment,the sleep quality of the two groups was improved,and the total PSQI score of the observation group after treatment was lower than that of the control group,with statistical significance(P<0.05).Conclusion:Iodine glycerin combined with minocycline hydrochloride has significant clinical advantages in the treatment of periodontitis,which is more conducive to reducing pain,improving periodontal indicators,and improving the sleep quality of patients.It can be further applied in clinical practice.