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混合型肝癌的诊治与影响预后因素研究

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摘要 混合型肝癌(combined hepatocellular-cholangiocarcinoma,cHCC-CCA)是临床较为少见的一种原发性肝癌类型,单一肿瘤组织中既有肝细胞癌(hepatocellular carcinoma,HCC)又有胆管细胞癌(chlangiocarcinoma,CC)结构,兼具HCC和CC特征,作为一种具有独特生物学行为的肿瘤,其流行病学、放射学和组织学特征,以及临床特点与经典HCC和肝内胆管细胞癌(intrahepaticcholangiocarcinoma,ICC)有所不同,生理学特性与ICC接近,但生物学行为较HCC更有侵袭性,常侵犯门静脉及胆管,发生淋巴结转移,术前确诊困难、恶性程度高、病程发展快、预后差.国外统计cHCC-CCA占原发性肝癌发病率的0.4%~14.2%[1],国内为1.8%~7.42%[2].
出处 《肝胆外科杂志》 2023年第1期73-80,共8页 Journal of Hepatobiliary Surgery
基金 上海市闵行区医学特色专科项目(2020MWFC03)。
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  • 1Xian-Huan Yu,Lei-Bo Xu,Hong Zeng,Rui Zhang,Jie Wang and Chao LiuAuthor Affiliations:Department of Hepato-Pancreato-Biliary Surgery and Department of Pathology,Sun Yat-Sen Memorial Hospital,Sun Yat-Sen University,Guangzhou 510120,China.Clinicopathological analysis of 14 patients with combined hepatocellular carcinoma and cholangiocarcinoma[J].Hepatobiliary & Pancreatic Diseases International,2011,10(6):620-625. 被引量:7
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