持续非卧床腹膜透析患者营养不良的影响因素

Influencing Factors of Malnutrition in Continuous Ambulatory Peritoneal Dialysis Patients

目的:研究持续非卧床腹膜透析患者的营养状态的影响因素。方法:回顾性分析2019年6月-2022年4月安徽医科大学第一附属医院收治的169例CAPD患者的临床资料。运用老年营养风险指数评估患者营养状态,将其分为营养正常组及营养不良组,比较两组患者的差别,分析各个变量与营养不良的相关性,并利用多因素logistic回归分析进行结果分析。结果:通过老年营养风险指数评估结果得出营养正常组83例(49.1%),营养不良组86例(50.9%)。两组年龄、血清白蛋白、血红蛋白、舒张压、碳酸氢根、尿酸、C反应蛋白、转铁蛋白饱和度水平比较,差异均有统计学意义(P<0.05)。多因素分析结果显示,血清白蛋白、碳酸氢根、尿酸为营养不良发生的保护因素,年龄为营养不良发生的独立危险因素(P<0.05)。结论:持续非卧床腹膜透析营养不良的发生率高,年龄是患者发生营养不良的独立危险因素,血清白蛋白、碳酸氢根、尿酸为患者发生营养不良的保护因素。

Objective:To study the influencing factors of nutritional status in patients with continuous ambulatory peritoneal dialysis(CAPD).Method:The clinical data of 169 patients with CAPD admitted to the First Affiliated Hospital of Anhui Medical University from June 2019 to April 2022 were retrospectively analyzed.Nutritional risk index was used to evaluate the nutritional status of the patients,and the patients were divided into normal nutrition group and malnutrition group.The differences between the two groups were compared,and the correlation between each variable and malnutrition was analyzed,multivariate logistic regression analysis was used to analyze the results.Result:According to the evaluation results of the geriatric nutrition risk index,83 cases(49.1%)in the normal nutrition group and 86 cases(50.9%)in the malnutrition group were obtained.There were significant differences in age,diastolic blood pressure,serum albumin,hemoglobin,bicarbonate,uric acid,C reactive protein,and transferrin saturation levels between the two groups(P<0.05).logistic regression analysis showed that age was independent risk factor for malnutrition in patients,and serum albumin,bicarbonate and uric acid were protective factors for malnutrition in patients(P<0.05).Conclusion:The incidence of malnutrition remains high in CAPD patients,age was independent risk factor for malnutrition,and serum albumin,bicarbonate and uric acid were protective factors for malnutrition.