摘要
瞬时受体电位通道(TRP通道)是位于细胞膜或细胞器膜上的一种特殊类型的非选择性阳离子通道家族,在黑素细胞中显著表达。本文综述近年来TRP通道在黑素细胞中的生理功能及其参与色素性皮肤病及黑素瘤病理过程的相关研究进展,为黑素相关疾病的防治提供新的理论基础。
Transient receptor potential(TRP)channels are a special type of non-selective cationic channel family located on the cell membrane or organelle membrane,and notably expressed in melanocytes.This review summarizes recent research progress in biological functions of TRP channels in melanocytes and their involvement in the pathological process of pigmented skin diseases and melanoma,so as to provide a new theoretical basis for the prevention and treatment of melanin-related diseases.
作者
陈怡
宋秀祖
Chen Yi;Song Xiuzu(Department of Dermatology,Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University,Hangzhou 310009,China;Department of Dermatology,Hangzhou Third People′s Hospital,Hangzhou 310009,China)
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
2023年第4期376-379,共4页
Chinese Journal of Dermatology
基金
国家自然科学基金(81872517)
浙江省基础公益研究计划项目(LGF18H110001)。
