1例死于肝硬化黑天鹅的病理诊断分析

Pathological Diagnosis of a Black Swan Died of Liver Cirrhosis

某单位发现1例观赏黑天鹅出现死亡,为探究其死亡原因,研究发现死亡前出现食欲减退、体重下降、腹水等症状。进行病理解剖和组织学检查,对病鹅的肝脏、心脏、脾脏、肾脏等进行切片和染色。病理解剖发现病鹅腹腔内有大量积液,肝脏表面呈现不规则结节,切面质地硬、颜色暗红。组织学检查发现肝脏明显萎缩、结构紊乱,肝窦扩张,肝细胞坏死、变性、空泡变性和纤维化;心肌组织发现弥漫性肌纤维坏死和间质纤维化,脾脏和肾脏未发现明显异常。可初步推断为肝硬化导致的腹水和多脏器功能障碍,可能与营养水平、寄生虫感染等因素有关,导致天鹅发生肝硬化。

A case of ornamental black swan was found dead in a unit,and to investigate the cause of death,this study revealed symptoms such as loss of appetite,weight loss,and ascites before death.Pathological autopsy and histological examination were performed,and the liver,heart,spleen and kidney of the diseased goose were sectioned and stained.The pathological autopsy found that there was a large amount offluid in the abdominal cavity of the sick goose,and the surface of the liver showed irregular nodules,with hard texture and dark red color on the cut surface.Histological examination found that the liver was obviously atrophied and structurally disturbed,the hepatic sinusoids were dilated,the hepatocytes were necrotic,degenerated,vacuolated and fibrotic;the myocardial tissue found diffuse myofiber necrosis and interstitial fibrosis,the spleen and kidneys did not find obvious abnormalities.In conclusion,it can be tentatively inferred that ascites and multiple organ dysfunction due to cirrhosis may be related to nutritional level,parasitic infection and other factors,thus leading to cirrhosis in swans.