超声检查胆囊结石直径和数量对胆囊收缩功能的影响

Investigation on the Influence of Size and Number of Gallbladder Stones on the Contractile Function of the Gallbladder by Ultrasonography

目的 探讨保胆取石手术中胆囊结石直径及数量对胆囊收缩功能的影响,为临床提供数据支持。方法 回顾性分析2016年3月30日-2019年12月21日期间门诊96例拟行保胆取石手术的胆囊结石患者,术前行常规超声检查。记录胆囊结石数量、胆囊结石最大径,分别测量空腹胆囊体积,进食后30、60、90、120分钟胆囊体积,并计算得出胆囊收缩率。胆囊收缩率≥80%为功能对照组,胆囊收缩率<80%为研究组,将患者分为对照组及研究组,比较2组间胆囊结石直径和数量对胆囊收缩功能影响。另外根据胆囊结石单发与多发分别进行分组分析,分组探讨胆囊结石直径对胆囊收缩功能的影响。结果 对照组与研究组中餐后120分钟胆囊体积大小有统计学意义,2组中胆囊结石平均直径≥(1.53±0.64)cm时,胆囊收缩功能下降;对照组多发结石病例占24.1%,单发结石病例占75.9%,研究组多发结石病例占71.4%,单发结石病例数占28.6%,单发结石对照组与研究组的胆囊结石直径对收缩功能无影响;多发结石对照组及研究组比较显示结石直径≥(1.53±0.60)cm,胆囊收缩功能明显下降。结论 超声检查胆囊结石的直径、结石的数量是影响胆囊的收缩功能的主要因素。

Objectives This study aims to explore the effect of the size and quantity of gallstones on the contractile function of gallbladder and provide data support for clinical practice. Methods A retrospective analysis was made on 96patients with gallstones who planned to undergo gallbladder preservation and lithotomy from March 30, 2016 to December 21, 2019. Routine ultrasonography was performed before operation. The number and the maximum diameter of gallstones were recorded.The gallbladder volume on an empty stomach and 30, 60, 90, and 120 minutes after eating was measured respectively, and the gallbladder contraction rate was calculated. The patients were divided into a control group and a study group. The effects of gallbladder stone diameter and number on gallbladder systolic function were compared between the two groups.In addition, single cases of gallbladder stones were divided into a control group and a research group.Patients with multiple gallbladder stones were divided into a control group and a research group. The effect of gallstone diameter on gallbladder systolic function was discussed in groups. Results There was significant difference in gallbladder volume 120 minutes after meal between the normal group and the study group.When the average diameter of gallbladder stone was larger than or equal to(1.53±0.64)cm, the gallbladder contraction function decreased.In the control group, the cases of multiple stones accounted for 24.1%, and the cases of single stones accounted for 75.9%. In the study group, the cases of multiple stones accounted for 71.4%, and the cases of single stones accounted for 28.6%. Compared between the two groups, multiple gallstones have an impact on gallbladder contraction function. The patients with single stone were further divided into a control group and a study group. The diameter of gallbladder stone had no effect on the contractile function. Patients with multiple stones were divided into a control group and a study group. The stone diameter was larger than or equal to(1.53±0.60)cm, and the gallbladder systolic function decreased significantly. Conclusions The diameter and quantity of gallstones are the main factors affecting the contractile function of gallbladder.