肉芽肿性小叶性乳腺炎伴发结节性红斑的诊疗进展

Progress in diagnosis and treatment of granulomatous lobular mastitis with erythema nodosum

肉芽肿性小叶性乳腺炎(granulomatous lobular mastitis, GLM)是一种病因和发病机制尚未阐明的乳腺良性疾病,好发于有生育哺乳史的育龄期女性,多表现为一侧乳房的疼痛性肿块。而结节性红斑的典型表现为双下肢红色触痛的皮下结节,它可作为GLM乳腺外症状出现于病人的病程中,这种伴发现象较为罕见。GLM伴发结节性红斑病人可能具有某些特殊的临床特征。本文对GLM伴发结节性红斑的病因、发病机制、临床表现、诊断和治疗方法等进行综述。

Granulomatous lobular mastitis(GLM) is a benign breast disease for which the etiology and pathogenesis have not yet been elucidated.It often presents as a single painful mass on one side of the breast.Erythema nodosum is typically a subcutaneous nodule of red tenderness in the lower extremities, which can coexist with GLM as an extra-mammary symptom.This phenomenon is relatively rare.Erythema nodosum associated with GLM may have some special clinical features.This article reviews the diagnosis and treatment progress of GLM with erythema nodosum.