新生化片联合卡孕栓对剖宫产子宫收缩性乏力产后出血的预防效果

Preventive Effect of Xinshenghua Tablets Combined with Carprost Suppository on Postpartum Hemorrhage Due to Cesarean Section Uterine Atony

目的探讨新生化片联合卡孕栓对剖宫产子宫收缩性乏力产后出血的预防效果。方法选择2019年1月至2021年1月我院收治的80例剖宫产子宫收缩性乏力患者,采用随机数表法分为A组(n=40)和B组(n=40)。A组接受单一卡孕栓治疗,B组在A组基础上加用新生化片治疗,对比两组产后出血预防有效率、产后2h及产后24h出血量及不良反应发生率。结果B组产后出血预防有效率(97.5%)高于A组(85%)(P<0.05)。B组产后2h及产后24h出血量低于A组(P<0.05)。B组不良反应发生率(2.5%)低于A组(15%)(P<0.05)。产后2周,B组子宫内膜厚度及子宫高度均低于A组(P<0.05)。结论新生化片联合卡孕栓可有效预防剖宫产子宫收缩性乏力产后出血,安全性较高,值得临床广泛应用及推广。

Objective To investigate the preventive effect of Xinshenghua Tablets combined with Carprost suppository on postpartum hemorrhage due to cesarean section uterine atony.Methods From January 2019 to January 2021,80 patients with cesarean section uterine atony who were treated in our hospital were selected and divided into group A(n=40)and group B(n=40)by random number table method.Group A received single carprost suppository therapy,and group B received Xinxinhua Tablet on the basis of group A.The effective rate of postpartum hemorrhage prevention,postpartum hemorrhage volume at 2 h and 24 h postpartum,and incidence of adverse reactions were compared between the two groups.Results The effective rate of postpartum hemorrhage prevention in group B(97.5%)was higher than that in group A(85%)(P<0.05).The bleeding volume in group B at 2h and 24h after delivery was lower than that in group A(P<0.05).The incidence of adverse reactions in group B(2.5%)was lower than that in group A(15%)(P<0.05).Two weeks after delivery,the endometrial thickness and uterine height in group B were lower than those in group A(P<0.05).Conclusion Xinshenghua Tablets combined with Carprost suppository can effectively prevent postpartum hemorrhage due to cesarean section uterine atony with high safety,which is worthy of wide clinical application and promotion.