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FFRCT对冠状动脉钙化斑块诊断价值的初步研究 被引量:2

Preliminary Study on the Diagnosis Value of FFRCT in the Coronary Calcified Plaque
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摘要 目的评价冠状动脉CT血管造影衍生的无创血流储备分数(FFRCT)诊断钙化病变的价值。方法对49例行冠脉CTA及CAG检查的病患资料进行回顾性分析。用Agatston积分法测量各钙化斑块,并分为A组(CACS≤100)、B组(100<CACS<400)和C组(CACS≥400)。利用数坤冠脉CT-FFR智能辅助诊断系统进行FFRCT值测定。计算三组FFRCT、CTA的诊断准确度、敏感度、特异度、阳性预测值及阴性预测值,构建ROC曲线对诊断效果评价。运用Kappa检验评价一致性。结果研究分析100处钙化斑块。在各组中FFRCT检出冠脉狭窄的真阳性率、Kappa值均高于CTA。A组FFRCT与CAG的一致性较好。与CCTA相比,各组FFRCT诊断的准确度、敏感度均较高;其中,FFRCT在C组准确度最高,为93.33%。各组FFRCT诊断的ROC曲线下面积均大于CTA。结论FFRCT对冠状动脉钙化病变具有较高的诊断效能,能为后续治疗提供更多信息,减少不必要的冠脉造影检查和血运重建术。 Objective To evaluate the value of noninvasive fractional flow reserve(FFRCT)generated by coronary CT angiography in diagnosis of calcification lesions.Methods The data of 49 patients who underwent coronary CTA and CAG from were analyzed retrospectively.The score of each calcified plaque with the Agatston integral method is used to divide the calcified plaque into group A(CACS≤100),group B(100<CACS<400)and group C(CACS≥400).The FFRCT value was performed using Shukun coronary CT-FFR intelligent auxiliary diagnosis system.Taking CAG as the gold standard,the diagnostic accuracy,sensitivity,specificity,positive predictive value and negative predictive value of FFRCT and CTA in the three groups were calculated.The construction of the ROC curve evaluated the diagnostic effect.Evaluation of consistency used Kappa test.Result The study analyzed 100 calcified plaques.The true positive rate of Coronary stenosis and Kappa value was detected by FFRCT in each group were higher than those detected by CTA.The consistency between FFRCT and CAG was better in group A.Compared with CCTA,the diagnostic accuracy and sensitivity of FFRCT in each group were higher.The diagnostic accuracy of FFRCT in group C was the highest,up to 93.33%.The area under the receiver operating characteristic curve of FFRCT in each group was greater than that of CTA.Conclusion FFRCT has a high diagnosis performance in coronary calcification,and can provide more information for subsequent treatment,reduce unnecessary coronary angiography and revascularization.
作者 鲍慧新 胡春峰 谢丽响 BAO Hui-xin;HU Chun-feng;XIE Li-xiang(Department of Radiology,Affiliated Hospital of Xuzhou Medical College,Xuzhou 221002,Jiangsu Provcince,China)
出处 《中国CT和MRI杂志》 2023年第4期79-81,共3页 Chinese Journal of CT and MRI
关键词 冠状动脉 钙化 CT血管成像 血流储备分数 Coronary Artery Calcification Computed Tomography Angiography Fractional Flow Reserve
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