四川省1666例境外输入性新型冠状病毒感染者的流行特征分析

Epidemiological characteristics of 1666 cases of imported novel coronavirus infection in Sichuan Province

目的分析四川省境外输入性新型冠状病毒(简称新冠病毒)感染者的流行病学特征,为疫情防控做支撑。方法从中国疾病预防控制信息系统收集2021年1月1日至2022年4月30日四川省报告的境外输入新冠肺炎感染者的个案信息、现场流行病学调查报告及实验室检测结果等。对感染者的人口学特征、病例分类、临床严重程度、入境前居住或旅行的国家或地区等特征进行整理和描述性及比较分析。结果2021年1月1日至2022年4月30四川省累计报告境外输入性新冠病毒感染者1666例,其中确诊病例1010例(60.62%),无症状感染者656例(39.38%)。确诊病例中普通型622例(61.58%);轻型388例(38.42%);无重型、危重型病例报告,无死亡病例;报告时间集中在2022年3月17日至2022年4月30日(632例,37.94%),以男性(1087例)、中青年(21~54岁,1349例)感染者为主,入境前居住或旅行的国家/地区主要有埃及、柬埔寨和阿尔及利亚等国家及中国香港地区。疫苗接种率为84.06%(1171/1393),接种2剂次人数占58.36%;54.08%(901例)的感染者入境当天报告新冠病毒核酸阳性结果。疫苗接种组的ORFlab基因、N基因Ct值均高于疫苗未接种组,差异有统计学意义(P<0.001)。结论四川省境外输入性感染者新冠病毒临床分型以普通型为主,疫苗接种率较高,疫苗接种对病毒载量和感染者临床特征有一定的积极的影响,可据此为外防输入管理措施提供一定参考。

Objective To analyze the epidemiological characteristics of imported COVID-19(novel coronavirus)infected persons in Sichuan Province,so as to provide support for epidemic prevention and control.Methods Case information,field epidemiological investigation report and laboratory test results of imported covid-19 infection individuals reported by Sichuan Province from January 1,2021 to April 30,2022 were collected from the China disease prevention and control information system.Demographic characteristics,case classification,clinical severity,countries or regions where the infected individuals lived or travelled before entering the country were analyzed.Results From January 1,2021 to April 30,2022,a total of 1666 cases of imported covid-19 infection from abroad were reported in Sichuan Province,including 1010(60.62%)confirmed cases and 656(39.38%)asymptomatic infections.Among the confirmed cases,622 cases(61.58%)were common type,and 388 cases(38.42%)were light type.There were no severe and dangerous cases and no deaths.The period of case reports is concentrated from March 17,2022 to April 30,2022(632cases,37.94%).Most cases were men(1087 cases)and young and middle-aged(aged 21-54,1349 cases).The countries/regions where they lived or travelled before entering the China mainly included Egypt,Cambodia,Algeria and Hong Kong,China.The vaccination rate was 84.06%(1171/1393),and the number of people vaccinated twice accounted for 58.36%.901 cases(54.08%)of infected persons reported positive results of covid-19 nucleic acid on the day of entry.The CT values of orflab gene and N gene in the vaccinated group were higher than those in the non-vaccinated group,and the difference was statistically significant(P<0.001).Conclusions The clinical typing of novel coronavirus is mainly common in the imported patients from abroad in Sichuan Province,and the vaccination rate is high.Vaccination has a certain positive impact on the viral load and the clinical characteristics of infected people,which can provide a certain reference for the management measures of external prevention import.