依托咪酯联合丙泊酚在老年无痛胃肠镜检查中的应用效果

Application Effect of Etomidate Combined with Propofol in Painless Gastroenteroscopy in Elderly Patients

目的:分析依托咪酯联合丙泊酚在老年无痛胃肠镜检查中的应用效果。方法:选取2020年6月-2022年6月在东莞市莞城医院行无痛胃肠镜检查的老年患者963例为观察对象,按随机数字表法将其分为对照组(n=481)与观察组(n=482)。对照组予以丙泊酚麻醉处理,观察组予以依托咪酯联合丙泊酚麻醉处理。比较两组患者相关麻醉效果指标、生命体征。结果:观察组麻醉诱导时间、停药后苏醒时间及定向力恢复时间等均短于对照组,差异有统计学意义(P<0.05);检查后,观察组收缩压、舒张压、心率等低于对照组,血氧饱和度高于对照组,差异有统计学意义(P<0.05);对照组检查时、检查后收缩压、舒张压、心率及血氧饱和度低于检查前,差异有统计学意义(P<0.05);观察组检查时收缩压、舒张压低于检查前,差异有统计学意义(P=0.000)。结论:老年患者进行无痛胃肠镜检查时,采用依托咪酯与丙泊酚麻醉进行处理能获得良好麻醉效果,可稳定患者生命体征。

Objective:To analyze the effect of etomidate combined with propofol in painless gastroenteroscopy in elderly patients.Methods:A total of nine hundred and sixty-three elderly patients who underwent painless gastroenteroscopy in Guancheng Hospital from June 2020 to June 2022 were selected as the observation objects,and were divided into control group(n=481)and observation group(n=482)according to random number table method.The control group was given propofol anesthesia,and the observation group was given etomidate combined with propofol anesthesia.Anesthesia effect indexes and vital signs were compared between the two groups.Results:The time of anesthesia induction,recovery time after drug withdrawal and recovery time of orientation in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After examination,systolic blood pressure,diastolic blood pressure and heart rate in the observation group were lower than those in the control group,while oxygen saturation was higher than that in the control group,with statistical significance(P<0.05).The systolic blood pressure,diastolic blood pressure,heart rate and oxygen saturation of the control group were lower during and after examination than before examination,and the differences were statistically significant(P<0.05).In the observation group,systolic blood pressure and diastolic pressure were lower than before,and the difference was statistically significant(P=0.000).Conclusion:In elderly patients undergoing painless gastroenteroscopy,the use of etomidate and propofol anesthesia can obtain good anesthetic effect and stabilize the vital signs of patients.