心理意象治疗脊髓损伤后神经性疼痛:神经影像学研究进展

Progresses of neuroimaging research on mental imagery for treating neuropathic pain after spinal cord injury

神经性疼痛(NP)是脊髓损伤(SCI)最常见并发症之一;药物和手术为主要治疗方法,但存在长期服药后药效下降、手术疗效差及术后复发等问题。心理意象(MI)可有效促进SCI患者运动功能康复、缓解NP,但其对于NP的疗效在不同患者之间存在差异,且具体机制尚不清楚。神经影像学可直观反映MI治疗前、治疗期间及治疗后大脑结构和功能变化,有助于理解MI调节NP的神经机制。本文就MI治疗SCI后NP的神经影像学研究进展进行综述。

Neuropathic pain(NP)is one of the most common complications of spinal cord injury(SCI),and drugs and surgery are the main therapeutic methods,but there are some problems such as the decline of efficacy after long-term administration,poor surgical efficacy and postoperative recurrence.Mental imagery(MI)could effectively promote the rehabilitation of motor function of SCI patients and relieve NP,but its efficacy was somehow different among NP patients,and the relative mechanisms remained unclear.Neuroimaging can directly reflect the changes of brain structure and function before,during and after MI treatment,hence being help for explaining the neural mechanisms of MI for regulating NP.The progresses of neuroimaging research on NP after MI treatment of SCI were reviewed in this article.