肝癌术后早期复发监测的研究进展

Research progress on the early recurrence monitoring after liver cancer surgery

原发性肝癌(PHC)简称肝癌,主要包括肝细胞癌(HCC)、肝内胆管癌(ICC)和混合型肝细胞癌-胆管癌(cHCC-CCA)三种病理学类型,是一种病死率、发病率均较高的恶性肿瘤。手术治疗是提高生存率的确切方式,但术后高复发率严重影响患者的预后生存。有效的监测可及时提醒我们疾病的复燃,对此,我们可利用生物标志物和复发预测模型等手段进行监测,及时发现病情的进展,以指导临床治疗。文章主要对HCC的术后早期复发的相关监测手段进行综述。

Primary hepatocellular carcinoma(PHC)is referred to liver cancer,mainly including three pathological types,hepatocellular carcinoma(HCC),intrahepatic cholangiocarcinoma(ICC)and combined hepatocellular cholangiocarcinoma(cHCC CCA),which is a malignant tumor with high mortality and morbidity.Surgical treatment is an effective way to improve the survival rate,but the high recurrence rate after surgery seriously affects patients'prognosis and survival.Effective monitoring can remind us of the relapse of the disease in time.In this regard,we can use biomarkers and recurrence prediction models to monitor the progress of the disease in time to guide clinical treatment.This article mainly reviews the relevant monitoring methods for early postoperative recurrence of HCC.