猫传染性腹膜炎诊断与治疗

Diagnosis and treatment of feline infectious peritonitis

猫传染性腹膜炎是由猫冠状病毒引起的渐进性、高致死性疾病。患猫可能出现食欲减退、精神沉郁、体重下降、发热、呼吸困难等症状。本文对两例幼龄公猫进行临床、血液学、影像学检查,均出现不同程度的胸腹腔积液,并伴有贫血、总胆红素升高、白蛋白与球蛋白比值降低等情况,结合猫冠状病毒核酸检测结果,病例1确诊为湿性猫传染性腹膜炎,病例2确诊为混合性猫传染性腹膜炎。对两病例使用核苷类似物GS-441524制剂并配合保肝药物,进行数月跟踪治疗,各项指标恢复正常,治疗效果显著。本文可为猫传染性腹膜炎的诊断和治疗提供一定的参考意义。

Feline infectious peritonitis(FIP),caused by feline coronavirus(FCoV),is a progressive and highly fatal disease.The cat may suffer from anorexia,depression,loss of weight,fever,and dyspnea.In this paper,two cases of cats were examined clinically,hematologically and imageologically.The results showed that both cases had different degrees of pleural and peritoneal effusion,anemia,increase of total bilirubin,and decreased ratio of albumin to globulin.Combined with the results of detection of cat coronavirus nucleic acid,case 1 was diagnosed as wet feline infectious peritonitis,and case 2 was diagnosed as mixed feline infectious peritonitis.Both of the cats were treated with nucleoside analogue GS-441524 in combination with hepatoprotective drugs for months.The therapeutic results showed that all indicators returned to normal,indicating that the cats had good therapeutic effect.The paper may provide some reference for the diagnosis and treatment of feline infectious peritonitis.