儿童阻塞性睡眠呼吸暂停与遗尿症关系的研究进展

Advances in the relationship between obstructive sleep apnea and enuresis in children

遗尿症(nocturnal enuresis,NE)和阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)均为儿童常见疾病,可引起各种社会心理问题,两者共患严重影响患儿身心健康。目前,OSA是否可导致NE以及具体的发病机制已有不少推测,OSA患儿可能由于体液因子的异常分泌、睡眠觉醒障碍、膀胱功能障碍、肥胖及精神心理因素等易患NE,其中体液因子的异常分泌和睡眠觉醒障碍可能起着至关重要的作用。研究发现对于OSA伴NE患儿,当存在上气道梗阻时,腺样体扁桃体切除手术可能是最佳的治疗方案。该文就NE与OSA之间的关系及治疗进行综述,旨在为临床上治疗OSA伴NE患儿提供参考意见。

Enuresis(NE)and obstructive sleep apnea(OSA)are common diseases in children,which often cause various social and psychological problems and the coexistence of both seriously affects the physical and mental health of children.At present,there have been many speculations about whether OSA can cause NE and the specific pathogenesis.OSA may be susceptible to NE due to abnormal secretion of humoral factors,sleep-wake disorders,bladder dysfunction,obesity,and psychosomatic factors,among which abnormal secretion of humoral factors and sleep-wake disorders may play a crucial role.In addition,it has been suggested that adenotonsillectomy may be the best treatment option for children suffering from OSA with NE when upper airway obstruction is present.This article summarizes the relationship between NE and OSA and how to treat them,aiming to provide a reference for the clinical treatment of OSA and NE.