精神分裂症浓缩版社会认知交互训练干预程序的设计及应用评价

Design and application evaluation of condensed version of social cognition interaction training intervention program in schizophrenia

目的 设计浓缩版社会认知交互训练(social cognition interaction training, SCIT)干预程序并探讨其对精神分裂症患者社会认知和社会功能的影响。方法 选取2018年6月—2020年3月在杭州市第七人民医院住院治疗的70例精神分裂症患者,采用随机数字表法分为干预组(浓缩版SCIT干预+药物治疗)和等待组(仅药物治疗),干预组31例和等待组32例完成干预后评估。干预前后采用阳性和阴性症状量表(PANSS)、个人和社会功能量表(PSP)、面部情绪识别任务(FEIT)及眼区心理阅读任务(ET)评估2组患者的精神病性症状、社会功能及社会认知水平。结果 实施干预后,2组患者PANSS总分及各因子分较干预前显著降低(均P<0.001),但干预组PANSS总分及各因子分较等待组差异无统计学意义(均P>0.05);干预后2组患者个人与社会功能量表、面部情绪识别任务及眼区心理阅读任务评分均较干预前有所提高,且干预组评分[(70.23±6.39)分,(25.35±1.52)分,(29.48±2.67)分]显著高于等待组[(62.69±9.24)分,(22.19±2.24)分,(26.72±2.57)分],差异均有统计学意义(均P<0.001)。结论 浓缩版SCIT干预可用于我国住院精神分裂症患者的临床干预,对该人群社会认知和社会功能有一定的康复疗效。

Objective To design a condensed version of social cognition interaction training(SCIT)intervention program and explore the effects of SCIT on social functioning and social cognition in patients with schizophrenia.Methods Seventy patients with schizophrenia who were hospitalized in Hangzhou Seventh People's Hospital from June 2018 to March 2020 were recruited.They were randomly divided into the intervention group(condensed version of SCIT plus drug treatment)and waiting-list group(only drug treatment).Thirty-one patients in the intervention group and 32 patients in the waiting-list group completed the post-assessment.Positive and negative symptom scale(PANSS),personal and social performance scale(PSP),face emotion identification task(FEIT)and reading the mind in the eyes task(ET)were used to evaluate the psychosis symptoms,social function and social cognitive level of patients in the two groups before and after intervention.Results After the intervention,the total score and factor scores of PANSS of two groups were significantly lower than those before intervention(all P<0.001),but there were no significant difference on the total score and factor scores of PANSS between the two groups(all P>0.05).The scores of PSP,FEIT and ET of two groups were significantly higher than those before intervention,and the scores of intervention group[(70.23±6.39)points,(25.35±1.52)points,(29.48±2.67)points]were higher than those of waiting-list group[(62.69±9.24)points,(22.19±2.24)points,(26.72±2.57)points],the differences were statistically significant(all P<0.001).Conclusion The condensed version of SCIT is a feasible and promising intervention method for improving social cognition and social functioning among inpatients with schizophrenia in China.