精神障碍患者感染新型冠状病毒后用药的潜在药物相互作用

Potential drug interactions in patients with mental disorders after infection with COVID-19

近期,新型冠状病毒感染疫情防控形势发生了变化。精神障碍患者感染新型冠状病毒(以下简称新冠病毒)后会面临以下的问题,新冠病毒感染相关治疗药物是否可与精神科治疗药物同时使用,药物间是否会发生药代或者药效方面的相互作用,如何规避药物相互作用带来的安全性风险。本文围绕上述问题,在汇总现有证据的基础上提出了一些建议,希望能给一线医生提供帮助。

Recently,the situation of the preventing and controlling of the novel coronavirus infection has changed.After patients with mental disorders are infected with the new coronavirus(hereinafter referred to as the new coronavirus),they will face the following problems:whether the drugs related to the new coronavirus infection can be used at the same time as the psychiatric drugs,and whether there will be pharmacokinetic or pharmacodynamic interactions between the medicines How to avoid the safety risks brought by drug interactions?Focusing on the above issues,this article puts forward some suggestions based on the summary of existing evidence,hoping to help front-line doctors.