轻度认知功能障碍人群语言功能受损的影响因素研究

Analysis on Influencing Factors of Language Impairment in Mild Cognitive Impairment Population

目的:调查轻度认知功能障碍(MCI)人群语言功能受损的影响因素,为早期干预社区人群语言功能受损提供参考依据。方法:选取2021年7—12月杭州市上城区笕桥街道社区120例≥40岁常驻居民作为研究对象,根据语言功能是否受损分为语言功能正常组(n=65)与语言功能受损组(n=55)。所有受试者完成基础资料调查表和蒙特利尔认知评估量表(MoCA),从中筛选出语言功能受损患者,使用多因素logistic回归分析探讨社区人群语言功能受损的影响因素。结果:语言功能受损组年龄大于语言功能正常组,差异有统计学意义(P=0.042);两组性别、文化程度比较,差异无统计学意义(P>0.05)。语言功能受损组语言评分低于语言功能正常组,MCI人数多于语言功能正常组,差异有统计学意义(P<0.001)。单因素分析提示,年龄、受教育时间、手机软件使用、粗粮食用对语言功能受损有影响,差异有统计学意义(P<0.05)。多因素logistic回归分析提示,粗粮食用、手机软件使用、受教育时间是轻度MCI人群语言功能受损的影响因素,差异有统计学意义(P<0.05)。结论:社区人群语言功能受损率较高,多食粗粮、使用手机软件、受教育时间长可能是语言功能受损的保护因素。

Objective:To investigate the influencing factors of language impairment in the population of mild cognitive impairment(MCI),and provide a basis for early intervention on language impairment in community populations.Methods:From July 2021 to December 2021,120 permanent residents aged≥40 years from Jianqiao Street Community of Shangcheng District of Hangzhou were selected as the study subjects.They were divided into normal language function group(n=65)and impaired language function group(n=55)according to whether language impairment was present.All subjects completed the basic data questionnaire and the Montreal Cognitive Assessment(MoCA)scale to screen out patients with language impairment.Multivariate logistic regression analysis was used to explore the influencing factors of language impairment in the community population.Results:The age in impaired language function group was high than that in the normal language function group,and the difference was statistically significant(P=0.042).There were no significant differences in gender and education level between the two groups(P>0.05).The language score in impaired language function group was lower than that in the normal language function group,and the number of MCI cases in impaired language function group was higher than that in the normal language function group,and the difference was statistically significant(P<0.001).Univariate analysis showed that the age,education time,use of mobile phone software use,and consumption of roughage had a significant effect on language impairment,and the difference was statistically significant(P<0.05).Multivariate logistic regression analysis showed that consumption of roughage,use of mobile phone software,and education time were the influencing factors of language impairment in the population with mild MCI,and the differences were statistically significant(P<0.05).Conclusion:The rate of language impairment in the community population is relatively high,and the more consumption of roughage,the use of mobile phone software,and the long education time may be the protective factors for language impairment.