摘要
结直肠癌肝转移的组织病理学生长方式与患者的预后相关,具有纤维增生型生长方式的患者预后较好。最新国际评分指南根据临床预后价值对组织病理学生长方式的评分临界值做了修改,将其分为完全性纤维增生型及非完全性纤维增生型两类。然而,肝转移瘤组织病理学生长方式与治疗的关系目前仍不清楚,应用无创性方法纵向评估生长方式的变化是未来发展的方向。本文就结直肠癌肝转移组织病理学生长方式的评分方法及其临床应用情况予以综述。
The histopathological growth pattern(HGP)of colorectal cancer liver metastasis(CRLM)is correlated with the prognosis of patients.Patients with desmoplastic HGP have a better prognosis.The latest international scoring guidelines have modified the cut-off value of HGP,and divides it into two types:complete desmoplastic HGP and incomplete desmoplastic HGP.However,the relationship between the HGPs and the treatment response to systemic treatment is still unclear.It is necessary to develop non-invasive methods to evaluate changes in HGP during treatment in the future.This paper reviews the new scoring consensus and clinical applications of HGP in CRLM.
作者
宋春霖
李文会
张子田
柴瑞梅
Song Chunlin;Li Wenhui;Zhang Zitian;Chai Ruimei(Department of Radiology,the First Hospital of China Medical University,Shenyang 110001,China;Institute of Cancer Research,the First Hospital of China Medical University,Shenyang 110001,China)
出处
《中华肝胆外科杂志》
CAS
CSCD
北大核心
2023年第3期234-237,共4页
Chinese Journal of Hepatobiliary Surgery
关键词
结直肠肿瘤
肝转移
组织病理学生长方式
Colorectal neoplasms
Liver metastasis
Histopathological growth pattern
