妊娠期阻塞性睡眠呼吸暂停筛查的研究进展

A Review of Recent Advances in Screening for Obstructive Sleep Apnea during Pregnancy

阻塞性睡眠呼吸暂停(OSA)是妊娠人群中常见的睡眠呼吸障碍性疾病,不仅与多种不良妊娠结局相关,也可能对母婴远期健康产生重要影响。目前诊断OSA的金标准多导睡眠监测在妊娠人群中难以大规模开展,导致绝大多数妊娠期OSA未能得到及时诊断。寻求其他筛查策略和筛查工具准确识别具有OSA风险的孕妇并进行及时诊治,对于改善不良妊娠结局具有重要意义。本文针对妊娠期OSA患病率、筛查现状、筛查时机、目标人群、筛查工具的研究进展进行综述,以期为妊娠期OSA的筛查提供参考和理论依据。

Obstructive sleep apnea(OSA)is a common sleep-disordered breathing in pregnant population,which is associated with adverse perinatal outcomes,and may have long-term health consequences on both mothers and children.Currently,the vast majority of pregnant women are underdiagnosed due to the difficulties in extensively performing polysomnography,a gold standard in OSA diagnosis.So it is essential to seek other screening strategies and tools to accurately identify pregnant women with high risk of OSA to improve their perinatal outcomes.We reviewed the prevalence of OSA in pregnancy,screening status,screening timing,target population and recent advances in screening tools,to providing a theoretical basis for implementing the screening in this group.