原发颈椎骨霍奇金淋巴瘤1例并文献复习

Primary osseous Hodgkin’s lymphoma originating from cervical spine:a case report and literature review

原发性骨霍奇金淋巴瘤(POHL)极为罕见,被定义为一种病变局限于骨骼或邻近软组织的恶性肿瘤,在确诊后6个月内没有任何区域上淋巴结或其他淋巴结外器官受累的证据。文章报告1例原发于颈椎的患者,通过临床表现、影像学、组织病理学和免疫组织化学,最终诊断为POHL,患者接受颈椎后路椎板切除术减压、肿瘤切除、ABVD化疗,但因病情加重死亡。POHL的整体患者较少,具体预后尚不清楚,可能与病变部位及范围、年龄等因素有关,应提高对起源于颈椎POHL的认识。

Primary osseous Hodgkin’s lymphoma(POHL)was defined as a malignancy with lesions confined to bone or adjacent soft tissue,there was no evidence of involvement of any supramolecular lymph nodes or other extrinsic lymph nodes within 6 months after diagnosis.We reported a case that originated from the cervical vertebra,after the diagnosis of clinical manifestations,imaging,histopathology and immunohistochemistry,the patient was finally diagnosed with POHL,the patient was treated with posterior cervical laminectomy decompression,tumor resection,and ABVD chemotherapy,but she died of exacerbation.The overall cases of POHL are few,and the specific prognosis of POHL is unknown,which may be related to the lesion site and scope,age and other factors.we should improve the knowledge of POHL originating from cervical spine.