苍艾挥发油对大学生焦虑情绪相关生理指标的影响

Effects of Cang-ai Volatile Oil on Physiological Indexes Related to Anxiety in College Students

目的实验室应激条件下诱发大学生焦虑情绪,并观察经鼻吸入苍艾挥发油(cang-ai volatile oil,CAVO)对该情绪相关生理指标的影响。方法招募108名符合纳入标准的大学生受试者,随机分为苍艾组、芳樟叶油组和空白组,36例/组。各组受试者均以“三位数连续减17”心算应激诱发焦虑情绪,剔除应激不响应者后,芳樟叶油组、苍艾组各30例、空白组31例,3组基线期和应激期焦虑相关指标无统计学差异,均衡可比。除空白组无精油干预外,其余2组分别经鼻吸入芳樟叶油、CAVO,监测试验的基线期、应激期、干预期和恢复期心搏总数、收缩压(systolic blood pressure,SBP)、舒张压(diastolic blood pressure,DBP)和心率变异性低频高频比值(low frequency high frequency ratio,LF/HF),并行组间与组内比较。结果①组内比较:3组应激期LF/HF、心搏总数、SBP和DBP高于基线期(P<0.05);空白组干预期与应激期比较无差异(P>0.05);苍艾组干预期LF/HF、心搏总数、SBP和DBP低于应激期(P<0.05),且与基线期、恢复期无明显差异(P>0.05);芳樟叶油组干预期LF/HF、SBP和DBP低于应激期(P<0.05),高于基线期和恢复期(P<0.05);②组间比较:苍艾组干预期LF/HF、SBP低于其它2组,DBP低于空白组(P<0.05)。结论实验室应激条件下,经鼻吸入CAVO后大学生焦虑情绪相关生理指标显著下降,可缓解应激诱发的焦虑情绪。

Objective The anxiety of college students was induced under laboratory stress,and the effects of inhalation of Cang-ai volatile oil(CAVO)on physiological indexes related to this emotion were observed.Methods 108 college students who met the recruitment criteria were selected and randomly divided into CAVO group,Cinnamomum camphora leaf oil group and blank group(36 cases/group).All subjects in each group were subjected to"three-digit continuous reduction of 17"mental calculation to induce anxiety.After excluding those who did not respond to stress,there were 30 cases in C.camphora leaf oil group,30 cases in CAVO group,and 31 cases in blank group.There was no statistical difference in anxiety related indexes in baseline and stress period in the three groups,and there was a balanced comparison.Except for the blank group without essential oil intervention,the other two groups were intranasally inhaled C.camphora leaf oil and CAVO respectively,the total heart beats,systolic blood pressure(SBP),diastolic blood pressure(DBP)and LF/HF in the baseline period,stress period,intervention period and recovery period of the trial were measured,and compared them between and within groups.Results Firstly,intra group comparison:LF/HF,total number of heart beats,SBP and DBP in the three groups were higher than those in the baseline period(P<0.05),there was no difference between intervention expectation and stress period in blank group(P>0.05).LF/HF,total heart beats,SBP and DBP in CAVO group during the intervention period were lower than those in the stress period(P<0.05),and there was no significant difference from the baseline period and recovery period(P>0.05).LF/HF,SBP and DBP in Cinnamomum camphora leaf oil group during intervention period were lower than those in the self-stress period(P<0.05),higher than those in the baseline period and recovery period(P<0.05).Secondly,comparison between groups:LF/HF and SBP in CAVO group group during the interver Period were lower thom those in other two groups,and DBP was lower than that in blank group(P<0.05).Conclusion Under the condition of laboratory stress,after inhaling CAVO through the nose,the physiological indicators related to anxiety of college students decreased significantly,which could alleviate the anxiety induced by stress.