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决明子对眼部疾病应用的研究进展

Research Progress on the Application of Cassia Seeds to Eye Diseases
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摘要 决明子是豆科植物决明或小决明的干燥成熟种子,味苦、甘、咸,性微寒,常用于目赤肿痛、羞明多泪、青盲内障等症的治疗.其含有多种生物活性成分,包括蒽醌类、萘并吡喃酮、多糖、蛋白质等多种抗氧化活性成分,具有抗炎抗氧化,抗细胞凋亡,维持眼部细胞表面离子平衡,降血糖,降眼内压的特性,这使其成为防治眼部疾病的潜在选择.本文阐述了决明子在眼部疾病中的应用,包括青光眼、白内障、糖尿病眼病及近视,并说明了决明子及其生物活性物质对各种眼科疾病治疗的潜在可行性. Cassia seeds are dried and mature seeds of legume Cassia or small Cassia,taste bitter,sweet,salty,slightly cold in nature.It is commonly used in the treatment of red eyes,swelling and pain,embarrassment and tears,glaucoma,and cataracts.It contains a variety of biologically active ingredients,including anthraquinones,naphthopyrones,polysaccharides,proteins and other antioxidants.It has the properties of anti-inflammatory,anti-oxidation,anti-apoptosis,maintaining ion balance on the surface of eye cells,lowering blood sugar,and lowering intraocular pressure,which makes it a potential choice for the prevention and treatment of eye diseases.This article describes the application of cassia seeds in ocular diseases,including glaucoma,cataract,diabetes ophthalmopathy and myopia,and illustrates the potential feasibility of cassia seeds and their bioactive substances in the treatment of various ophthalmic diseases.
作者 李玉兰 董鑫宇 桑佳煜 刘世丹 韩一永 薛然 罗进城 祝丽玲 LI Yu-lan;DONG Xin-yu;SANG Jia-yu;LIU Shi-dan;HAN Yi-yong;XUE Ran;LUO Jin-cheng;ZHU Li-ling(School of Public Health,Jiamusi University,Jiamusi 154007,China;Key Laboratory of Gout Research,Heilongjiang Province,Jiamusi 154007,China)
出处 《辽宁大学学报(自然科学版)》 CAS 2023年第1期72-77,共6页 Journal of Liaoning University:Natural Sciences Edition
基金 黑龙江省教育厅基本科研业务费项目(2020-KYYWF-0300) 黑龙江省大学生创新创业项目(20211022160) 佳木斯大学公共卫生学院“儿童青少年近视防控”专项任务课题(GW202202)。
关键词 决明子 青光眼 白内障 糖尿病眼病 近视 cassia seeds glaucoma cataract diabetes ophthalmopathy myopia
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