基于“阳化气、阴成形”思想探讨激活脂肪组织产热在肥胖症辨治中的应用

Exploring clinical application of activating fatty thermogenesis in obesity treatment based on the theory of“yang transforming into qi,while yin constituting form”

从“阳化气、阴成形”的视角重新认识肥胖症的成因,并将现代分子生物学机制与传统中医理论结合,梳理探讨“转静为动、化形为气”理念在肥胖症辨治中的应用。形气理论指导下的中医方药内涵分为补气化形使精微归于正化、益火之源以消阴翳之形、苦辛开结以畅气调形3个方面,均围绕激活脂肪产热的核心机制,发挥改善肥胖症的作用。

Based on the perspective of“yang transforming qi,while yin constituting form”,we re-understood the causes of obesity.Meanwhile,we combined modern molecular biology mechanism and traditional Chinese medicine theory to discuss the application of“transforming static into dynamic and form into qi”in the obesity treatment.The connotation of traditional Chinese medicine prescriptions guided by form-qi theory could be explained from 3 aspects:replenishing qi and transforming blood to make the essential substance transforming into the normal pattern,boosting source of fire for eliminating abundance of yin,and resolving the hard mass with bitter-pungent medicines to adjust qi and blood circulation.All of them played a role in improving obesity by revolving the core mechanism of activating fat thermogenesis.