丙泊酚联合依托咪酯麻醉应用于老年患者胃肠镜检查的效果研究

Clinical Effect of Propofol Combined with Etomidate for Gastrointestinal Endoscopy Anesthesia

目的:探讨丙泊酚联合依托咪酯麻醉应用于老年患者胃肠镜检查的效果。方法:选取2021年10月—2022年5月于我院就诊的150例进行胃肠镜检查老年患者作为研究对象,根据治疗方式不同分为对照组(采用丙泊酚麻醉)和治疗组(采用丙泊酚联合依托咪酯麻醉),各75例。比较两组麻醉状态(麻醉诱导时间、苏醒时间、定向力恢复时间、无痛胃肠镜检查用时)、麻醉前后临床指标(收缩压、舒张压、血氧饱和度、平均动脉压、心率、呼吸频率)以及安全性。结果:治疗组麻醉诱导时间、苏醒时间以及定向力恢复时间短于对照组(P<0.05);两组无痛胃肠镜检查用时比较,差异无统计学意义(P>0.05)。治疗后,治疗组收缩压、舒张压、血氧饱和度、平均动脉压以及心率高于对照组,呼吸频率低于对照组(P<0.05)。治疗组不良反应总发生率为4.00%,低于对照组的16.00%(P<0.05)。结论:丙泊酚联合依托咪酯麻醉可以缩短患者苏醒时间,改善患者的血压和心率,安全性较高。

Objective:To investigate the clinical effect of propofol combined with etomidate on gastrointestinal anesthesia in elderly patients.Methods:A total of 150 elderly patients with gastrointestinal endoscopy in our hospital from October 2021 to May 2022 were selected as the research objects.According to different treatment methods,they were divided into the control group(using propofol anesthesia)and the treatment group(using propofol+etomidate anesthesia),with 75 cases in each group.The anesthesia state(anesthesia induction time,recovery time,orientation recovery time,painless gastroscopy time),clinical indexes(systolic blood pressure,diastolic blood pressure,oxygen saturation,mean arterial pressure,heart rate,respiratory rate)and safety before and after anesthesia were compared between the two groups.Results:The anesthesia induction time,recovery time and directional force recovery time in the treatment group were shorter than those in the control group(P<0.05);there was no significant difference in the use of painless gastrointestinal endoscopy between the two groups(P>0.05).After treatment,the systolic blood pressure,diastolic blood pressure,oxygen saturation,mean arterial pressure and heart rate in the treatment group were higher than those in the control group,and the respiratory rate was lower than that in the control group(P<0.05).The total incidence of adverse reactions in the treatment group was 4.00%,which was lower than 16.00%in the control group(P<0.05).Conclusion:Propofol combined with etomidate in elderly patients with gastroenteroscopic anesthesia can shorten the recovery time of patients,improve the blood pressure and heart rate of patients,and has high safety.