老年高血压患者并发阵发性心房颤动的影响因素分析

Analysis of Influencing Factors of Paroxysmal Atrial Fibrillation in Elderly Patients with Hypertension

目的:分析老年高血压患者并发阵发性心房颤动(PAF)的影响因素。方法:选取郑州大学附属洛阳中心医院2019年9月至2022年9月收治的94例老年高血压患者作为研究对象,评估患者合并PAF情况,分为并发组、未并发组;自拟一般资料调查问卷,比较两组患者相关资料,采用logistic回归分析老年高血压患者并发PAF的影响因素。结果:94例老年高血压患者经评估,有30例并发PAF,并发率为31.91%。并发组左房内径(LAD)、左室后壁厚度(LVPWT)、中性粒细胞/淋巴细胞比值(NLR)均大于未并发组,血清超敏C反应蛋白(hs-CRP)水平高于未并发组,且低密度脂蛋白胆固醇(LDL-C)值小于未并发组,差异具有统计学意义(P<0.05);两组其他一般资料比较,差异无统计学意义(P>0.05)。多因素logistic回归分析结果显示,LAD、LVPWT、NLR值异常升高、hs-CRP水平高、LDL-C偏低均为老年高血压患者并发PAF的危险因素。结论:老年高血压患者并发PAF风险较高,可能受LAD、LVPWT、NLR值异常升高、hs-CRP水平高、LDL-C偏低因素影响。

Objective To analyze the influencing factors of paroxysmal atrial fibrillation(PAF)in elderly patients with hypertension.Methods A total of 94 elderly hypertension patients admitted to Luoyang Central Hospital Affiliated to Zhengzhou University from September 2019 to September 2022 were selected as research objects.The patients with PAF were evaluated and divided into concurrent group and non-concurrent group.The general data questionnaire was designed by ourselves,and the relevant data of the two groups were compared.The influencing factors of PAF in elderly hypertension patients were analyzed by logistic regression.Results Among 94 elderly patients with hypertension,30 cases were found to be complicated by PAF,the complication rate was 31.91%.The left atrial inner diameter(LAD),left ventricular posterior wall thickness(LVPWT),neutrophil/lymphocyte ratio(NLR),in the concurrent group were greater than those in the non-concurrent group.The level of serum hypersensitive C-reactive protein(hs-CRP)was higher than that in the non-concurrent group,and the value of low density lipoprotein cholesterol(LDL-C)was lower than that in the non-concurrent group.The differences were statistically significant(P<0.05).There was no significant difference in other general information between the two groups(P>0.05).Multivariate logistic regression analysis showed that abnormal increase of LAD,LVPWT and NLR,high hs-CRP level and low LDL-C were all risk factors for complicated PAF in elderly patients with hypertension.Conclusion The risk of complicated PAF in elderly patients with hypertension is higher,which may be influenced by abnormal increase of LAD,LVPWT,NLR,high hs-CRP level and low LDL-C.