腹腔镜胆囊切除手术使用七氟烷和瑞芬太尼复合麻醉的疗效及作用分析

Effect Analysis of Sevoflurane and Remifentanil Combined Anesthesia in Laparoscopic Cholecystectomy

目的 探究腹腔镜胆囊切除手术使用七氟烷和瑞芬太尼复合麻醉的疗效及作用。方法 随机选取2020年5月—2021年5月新泰市人民医院接收的70例腹腔镜胆囊切除手术患者为研究对象,随机分为对照组(35例)与观察组(35例);前者予以丙泊酚和瑞芬太尼复合麻醉干预;后者予以七氟烷和瑞芬太尼复合麻醉干预;比较两组患者麻醉效果、麻醉时间指标、并发症发生率、拔管后的清醒状况。结果 麻醉干预后,观察组麻醉效果(97.14%)优于对照组(71.43%),差异有统计学意义(χ^(2)=8.737,P=0.003)。观察组患者意识恢复时间、清醒时间、定向力恢复时间短于对照组,差异有统计学意义(t=13.515、16.491、24.962,P<0.001)。观察组并发症发生率低于对照组,差异有统计学意义(χ^(2)=8.737,P=0.003)。观察组警觉/镇静(OAA/S)评分高于对照组,差异有统计学意义(t=15.179,P<0.05)。结论 对行腹腔镜胆囊切除手术的患者采用七氟烷和瑞芬太尼复合麻醉的效果显著,可提升患者麻醉效果,缩短患者意识恢复时间、清醒时间以及定向力恢复时间,并减少患者并发症发生率。

Objective To investigate the effects of sevoflurane and remifentanil combined anesthesia in laparoscopic cholecystectomy.Methods 70 patients with laparoscopic cholecystectomy admitted to Xintai People´s Hospital from May 2020 to May 2021 were randomly selected as the research object and randomly divided into control group(35 cases)and observation group(35 cases).The former was given propofol and remifentanil combined anesthesia intervention;the latter was treated with sevoflurane and remifentanil combined anesthesia.Anesthesia effect,anesthesia time index,complication rate and wakefulness after extubation were compared between the two groups.Results After anesthesia intervention,the anesthetic effect of the observation group(97.14%)was better than that of the control group(71.43%),the difference was statistically significant(χ^(2)=8.737,P=0.003).The recovery time of consciousness,wakeful time and orientation in the observation group was shorter than that in the control group,and the differences were statistically significant(t=13.515,16.491,24.962,P<0.001).The complication rate of the observation group was lower than that of the control group,and the difference was statistically significant(χ^(2)=8.737,P=0.003).Vigilance/sedation(OAA/S)score in observation group was higher than that in control group,and the difference was statistically significant(t=15.179,P<0.05).Conclusion For patients undergoing laparoscopic cholecystectomy,sevoflurane and remifentanil combined anesthesia has significant effects,which can improve the anesthesia effect,shorten the recovery time of consciousness,wakefulness and orientation,and reduce the incidence of complications.