妊娠期磁共振成像安全性评价

Safety evaluation of magnetic resonance imaging during pregnancy

妊娠期磁共振成像(MRI)临床使用正在增加,因为它无需电离辐射即可提供高质量的横断面解剖和病理学描述。MRI通常用于评估孕妇急性腹痛和盆腔疼痛、神经系统异常、胎儿/胎盘异常、肿瘤、感染和(或)心血管异常等。然而,迄今为止,对妊娠期MRI安全性的了解,特别是关于能够穿过胎盘屏障的钆对比剂(GBCA)的管理仍然有限,这使得人们对母亲和胎儿的健康方面可能出现的负面影响产生了担忧。因此,本文综述了国内外MRI和GBCA在妊娠期间应用的安全性以及当前社会指南的建议等,为妊娠期MRI的应用和正确认识提供一定参考。

The use of magnetic resonance imaging(MRI)during pregnancy is increasing because it provides high-quali-ty cross-sectional anatomical and pathological descriptions without ionizing radiation.MRI is commonly used to evalu-ate the situations of acute abdominal and pelvic pain,nervous system abnormalities,fetal/placental abnormalities,tumors,infections,and/or cardiovascular abnormalities of the pregnant women.However,to date,the understanding of the safety of MRI during pregnancy,particularly regarding the administration of gadolinium based contrast agent(GBCA),which is capable of crossing the placental barrier,remains limited,raising the concerns about the possible negative effects on the health of the mother and fetus.Therefore,this paper reviews the safety of MRI and GBCA ap-plication during pregnancy at home and abroad,as well as the recommendations of current social guidelines,so as to provide some references for the application and correct understanding of MRI during pregnancy.