冠状动脉周围脂肪组织的影像学研究进展

maging research progress in pericoronary adipose tissue

冠状动脉周围脂肪组织(PCAT)通过在细胞水平上与血管壁的“双向通信交流”,在血管炎症和冠状动脉粥样硬化的发生发展中起着关键作用。冠状动脉CT血管成像(CCTA)能通过检测血管周围脂肪衰减指数(FAI)定量评估PCAT的密度,用于可视化或量化冠状动脉血管炎症,有助于早期识别具有较高冠状动脉炎症负担的患者,对于预防心血管疾病的发生与发展具有重要意义。本文对近年来PCAT的影像学研究进行归纳总结。

The pericoronary adipose tissue(PCAT)plays a key role in the development of vascular inflammation and coronary atherosclerosis through“bidirectional communication”with the vascular wall at the cellular level.Coronary computed tomography angiography(CCTA)can quantitatively assess the density of PCAT by detecting the perivascular fat attenuation index(FAI),which can be used to visualize or quantify coronary vascular inflammation and help to early identify patients with high burden of coronary inflammation,and is of great significance for preventing the occurrence and development of cardiovascular diseases.This review article summarized the imaging studies on PCAT in recent years.