突发性聋患者血氧饱和度与耳蜗死区的相关性

Correlation between oxygen saturation and cochlear dead regions of sudden deafness

目的分析突发性聋患者耳蜗死区及分布情况,并进一步探讨其与血氧饱和度的相关性。方法应用均衡噪声阈值检测法及睡眠呼吸监测检测73例(112耳)突发性耳聋患者耳蜗死区及血氧饱和度,并初步探讨其是否相关。结果73例突发性聋患者有42.0%(47/112)受检耳存在耳蜗死区,不同听力曲线突发性聋患者中耳蜗死区检出率差异有统计学意义(P<0.05)。不同血氧饱和度、病程突发性聋患者中耳蜗死区检出率差异有统计学意义(P<0.05)。logistic回归显示血氧饱和度、病程与耳蜗死区相关(P<0.05)。结论本研究发现突发性聋患者存在耳蜗死区,主要分布在高频区,血氧饱和度、病程可能是出现耳蜗死区的影响因素。

Objective To investigate the cochlear dead regions and the distribution thereof in patients with sudden deafness and further investigate their correlation with oxygen saturation.Methods The cochlear dead regions and oxygen saturation of 73 patients(112 ears)with sudden deafness were detected by threshold-equalizing noise test and sleep apnea monitor,and the correlation between cochlear dead regions and deafness was preliminarily discussed.Results Among 73 case with sudden deafness,42.0%(47/112)of the ears had cochlear dead regions.The detection rate of cochlear dead regions in patients with sudden deafness with different hearing curves was statistically significant(P<0.05).The detection rate of cochlear dead regions in patients with sudden deafness with different oxygen saturation and in different courses of disease were statistically significant(P<0.05).Logistic regression analysis showed that oxygen saturation and the course of disease were correlated with cochlear dead regions(P<0.05).Conclusion This study found that cochlear dead regions exist in patients with sudden deafness,which are mainly distributed in the high-frequency region.The oxygen saturation and course of disease may be the influencing factors of cochlear dead regions.