腹股沟疝修补术对男性精子质量影响的Meta分析

Effect of inguinal herniorrhaphy on male sperm quality:A Meta-analysis

目的分析腹股沟疝修补术对男性精子质量的影响。方法在PubMed、EMBASE、The Cochrane Library、Web of Science、知网、万方、Sinomed等数据库中检索文献,时间从2000年1月至2022年6月。收集国内外有关接受腹股沟疝修补术的患者术前术后的精液质量变化的文献,按照纳排标准筛选文献,提炼数据后采用Review Manager 5.3统计软件分析。结果共纳入9项队列研究。Meta分析结果显示:腹股沟疝修补术会降低男性的精子浓度,而对精子总数、射精量、精子向前运动(%)、睾丸动脉阻力指数和睾丸体积无明显影响。结论腹股沟疝修补术会降低男性精子浓度,而对其他精液参数无明显影响,这需要更多大样本量和更长随访时间的前瞻性研究来证明。

Objective To analyze the effect of inguinal herniorrhaphy on male sperm quality.Methods Medical literature was retrieved from such databases as PubMed,EMBASE,Cochrane Library,Web of Science,CNKI,Wanfangdata and Sinomed from January 2000 to December 2021.Domestic and foreign literatures on changes in sperm quality of patients before and after inguinal hernia repair were collected.The literature was screened according to the inclusion/exclusion criteria,and then analyzed by Review Manager 5.3 statistical software.Results A total of 9 cohort studies were included.The Metaanalysis Results showed that inguinal herniorrhaphy reduced male sperm concentration,but had no significant effect on total sperm count,volume of ejaculation,forward motile sperm(%),testicular arterial resistance index,and testicular volume.Conclusion Inguinal herniorrhaphy will reduce male sperm concentration,but has no significant effect on other semen parameters,which requires a randomized prospective study with larger sample size and longer follow-ups for confirmation.