心房颤动与认知障碍相关性的研究进展

Research progress in correlation between atrial fibrillation and cognitive impairment

心房颤动(简称房颤)与认知障碍关系密切。临床研究证据显示房颤增加1.5~2.5倍的认知障碍风险,其导致的脑组织功能和结构异常是认知障碍的主要原因;抗凝、室率控制和节律控制等治疗策略可显著降低认知障碍的风险。但房颤相关认知障碍并未被临床重视,且常被忽视。本文对两者关系进行综述,为防治房颤相关认知障碍提供资料。

Atrial fibrillation(AF)is closely associated with cognitive impairment.Evidence from clinical research reveals that AF increases the risk of cognitive impairment by 1.5-2.5 times;the functional and structural abnormalities of the brain tissues caused by AF are the major cause of cognitive impairment;anticoagulation,ventricular rate control rhythm control,and other therapeutic strategies can significantly reduce the risk of cognitive impairment.However,AF-associated cognitive impairment has not received adequate clinical attention and is often overlooked.This article reviews the relationship between the two to provide data for preventing and treating AF-associated cognitive impairment.