The presence of functional blood vessels in the ischemic core provides a therapeutic target for stroke recovery

Ischemic stro ke occurs when a blood vessel in the brain is occluded.In the immediate aftermath.blood flow becomes deficient in regions supplied by the blocked vessel.This leads to the development of a core region,where blood flow is reduced to <30% and injury occurs rapidly,and a penumbral region,where blood flow is reduced to a level that is not capable of supporting neuronal function,but is sufficient to maintain cell viability(Morris et al.,2023).