基于津液亏虚与湿邪化生的关系论治干燥综合征

Treatment of Sj gren′s Syndrome Based on Relationship Between Body Fluid Deficiency and Dampness

干燥综合征的病机中存在津液亏虚和湿邪化生的双重矛盾,两者在疾病病机衍化中可同时出现,且又密切联系。津液亏虚是湿邪化生之重要病理基础,湿邪化生又是津液亏虚病机进展之动因,两者共同推动病情发展,最终协同酿生他邪,亢害机体。干燥综合征的病机演化包括津液亏虚、阴虚夹湿、阴虚夹湿热、气阴两虚夹湿热、气阴两虚夹湿热瘀毒五个阶段,治疗时应以滋阴化湿为基本治法,在疾病所处的不同阶段,或清热、或益气、或化瘀、或解毒以治之。

There is a dual contradiction between deficiency of body Fluid and production of Dampness in pathogenesis of Sj gren′s syndrome.The two can occur simultaneously and are closely related in the evolution of the disease pathogenesis.The deficiency of body Fluid is an important pathological basis for the production of Dampness evil factor,and the production of Dampness is the driving force for the pathogenesis progression of the body Fluid deficiency.Together,the two promote the development of the disease,ultimately leading to the synergistic breeding of other pathogens and the harm to the body.The pathogenesis evolution of Sj gren′s syndrome includes five stages:body Fluid deficiency,Yin deficiency with Dampness,Yin deficiency with Dampness Heat,Qi and Yin deficiency with Dampness Heat as well as Qi and Yin deficiency with Dampness Heat and stasis toxin.Therefore,when treating Sj gren′s syndrome,the basic treatment method should be nourishing Yin and transforming Dampness.At different stages of the disease,it can be treated by clearing Heat,supplementing Qi,resolving blood stasis,or detoxifying.