水床式鸟巢俯卧位通气联合口腔免疫疗法在极低出生体重儿机械通气中的应用效果

Application effect of waterbed type bird′s nest prone position ventilation combined with oral immunotherapy in very low birth weight infants

目的探讨水床式鸟巢俯卧位通气联合口腔免疫疗法在极低出生体重儿机械通气中的应用效果。方法选取2020年7月至2021年6月赣州市人民医院儿科收治的需机械通气的58例极低体重儿作为研究对象,按照随机数字表法分为观察组和对照组,每组各29例,对照组患儿采取水床式鸟巢俯卧位通气干预,观察组患儿采取水床式鸟巢俯卧位通气联合口腔免疫疗法干预,比较两组患儿各项症状改善情况,同时分析两组患儿的并发症发生率,观察两组患儿的体重恢复状况。结果观察组患儿的体温低于对照组,单日增加体重重于对照组,单日进奶增加量多于对照组,住院时间短于对照组,差异有统计学意义(P<0.05);观察组患儿的喂养不耐受、皮肤破溃、呼吸暂停、硬肿及窒息发生率均低于对照组,差异有统计学意义(P<0.05);观察组患儿的体重恢复时间短于对照组,体重增长重于对照组,差异有统计学意义(P<0.05);干预后,观察组患儿的各生存质量维度评分均高于对照组,差异有统计学意义(P<0.05)。结论水床式鸟巢俯卧位通气联合口腔免疫疗法在极低出生体重儿机械通气中能够有效地改善患儿的各项临床症状,并且降低患儿的并发症发生率,同时患儿的体质恢复状况明显较好,达到了理想的临床效果,值得广泛运用于出生体重儿照料当中。

Objective To investigate the application effect of waterbed type bird's nest prone position ventilation combined with oral immunotherapy in very low birth weight infants.Methods A total of 58 very low birth weight children who needed mechanical ventilation admitted to the Department of Pediatrics of Ganzhou People's Hospital from July 2020 to June 2021 were selected as the research objects.According to the random number table method,they were divided into observation group and control group,with 29 cases in each group.The control group was received waterbed type bird's nest prone position ventilation intervention,and the observation group was received waterbed type bird's nest prone position ventilation combined with oral immunotherapy intervention.The improvement of symptoms of the two groups was compared,and the incidence of complications of the two groups was analyzed,and the weight recovery of the two groups was observed.Results The body temperature of children in the observation group was lower than that in the control group,the weight gain in a single day was higher than that in the control group,the increase in milk intake in a single day was more than that in the control group,and the hospitalization time was shorter than that in the control group,and the differences were statistically significant(P<0.05).The incidences of feeding intolerance,skin ulceration,apnea,swelling and asphyxia in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The weight recovery time of the observation group was shorter than that of the control group,and the weight gain was heavier than that of the control group,and the differences were statistically significant(P<0.05).After intervention,the scores of all dimensions of quality of life of children in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Waterbed type bird's nest prone position ventilation combined with oral immunotherapy can effectively improve the clinical symptoms of very low birth weight infants in mechanical ventilation,and reduce the incidence of complications in children,at the same time,the children's physical recovery is significantly better,achieving the ideal clinical effect,it is worthy of being widely used in the care of birth weight infants.