子宫内膜癌的影像组学研究进展

Research progress of radiomics in endometrial cancer

子宫内膜癌(endometrial cancer, EC)是最常见的妇科恶性肿瘤之一,其治疗方法依赖于准确的术前影像和临床评估。影像组学通过从医疗图像中高通量地提取定量特征,将图像信息转换为直观的数据来反映肿瘤内部异质性信息。基于MRI的影像组学可以无创精准地对EC患者进行术前预评估,有助于临床医生为患者选择合适的治疗方案。本文旨在介绍影像组学的基本概念和流程,对EC在风险分层、组织病理学分级、肌层浸润深度、宫颈间质浸润、淋巴血管间隙浸润、淋巴结转移、预后和鉴别诊断等领域的影像组学研究现状进行综述,并对未来研究进行初步展望,以期为临床提供EC精准诊疗的影像指导。

Endometrial cancer is one of the most common gynecologic malignancies,and its treatment relies on accurate preoperative imaging and clinical evaluation.Radiomics transforms image information into intuitive data to reflect tumor internal heterogeneity by extracting quantitative features from medical images with high throughput.MRI-based radiomics can perform preoperative pre-assessment of patients with endometrial cancer non-invasively and accurately,helping clinicians to choose the appropriate treatment plan for patients.This article aims to introduce the basic concepts and processes of radiomics,review the current status of radiomics research for endometrial cancer in the fields of risk stratification,histopathological grade,myometrial invasion depth,cervical space invasion,lymphovascular space invasion,lymph node metastasis,prognosis and differential diagnosis,and make a preliminary prospect for future research,in order to provide imaging guidance value for the precise diagnosis and treatment of endometrial cancer in clinical practice.