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胃癌患者循环肿瘤细胞检测的临床意义 被引量:3

Clinical significance of circulating turbroid tumor cell detection in patients with gastric cancer
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摘要 探讨胃癌患者检测循环肿瘤细胞(CTCs)的临床意义。选取2018年1月至2019年1月滨州医学院附属淄博市中心医院胃肠外科收治的胃癌患者60例(观察组)和同期26例良性胃病患者(对照组)作为研究对象。检测两组患者治疗前CTCs水平,同时检测胃癌组患者肿瘤标志物CEA水平。胃癌组患者CTCs阳性率为68.33%(41/60),明显高于胃良性疾病患者组(7.69%,2/26),差异具有统计学意义(P<0.05);胃癌组CTCs水平与患者年龄、性别、肿瘤直径大小、分化程度、淋巴结转移无关(P>0.05);与肿瘤TNM分期、脉管侵犯、远处转移密切相关(P<0.05)。CTCs对胃癌的诊断阳性率为63.33%(38/60),CEA对胃癌的诊断阳性率为31.67%(19/60),CTC联合CEA对胃癌的诊断阳性率为73.33%(44/60)。胃癌患者CTCs水平显著升高;CTCs水平与胃癌临床分期、脉管癌栓、远处转移相关;CTCs联合CEA检测可以提高早期胃癌的阳性率。
作者 路帅 崔庆 赵强 周成富 刘承奎 薛令凯 毛鸿屯 LU Shuai;CUI Qing;ZHAO Qiang
出处 《中国现代普通外科进展》 CAS 2023年第4期304-306,309,共4页 Chinese Journal of Current Advances in General Surgery
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