认知行为疗法联合阿戈美拉汀对抑郁症患者临床疗效、抑郁程度及自杀意念的影响

Impact of Cognitive Behavior Therapy Combined with Agomelatine on Clinical Efficacy,Depression Degree and Suicidal Ideation of Patients with Depression

目的探讨认知行为疗法(CBT)联合阿戈美拉汀对抑郁症患者临床疗效、抑郁程度及自杀意念的影响。方法选取2020年5月至2022年4月我院收治的60例抑郁症患者,随机分为两组各30例。对照组给予阿戈美拉汀治疗,观察组给予CBT联合阿戈美拉汀治疗。比较两组的临床疗效、抑郁程度及自杀意念。结果观察组的治疗总有效率为86.67%,显著高于对照组的63.33%(P<0.05)。治疗后,两组的BDI-21评分、SIOSS评分均显著低于治疗前,且观察组的BDI-21评分、SIOSS评分均显著低于对照组(P<0.05)。结论CBT联合阿戈美拉汀治疗抑郁症患者可明显提升临床疗效,降低抑郁程度,减轻自杀意念。

Objective To explore the impact of cognitive behavior therapy(CBT)combined with agomelatine on clinical efficacy,depression degree and suicidal ideation of patients with depression.Methods 60 patients with depression admitted to our hospital from May 2020 to April 2022 were selected and randomly divided into two groups,with 30 cases in each group.The control group was treated with agomelatine,and the observation group was treated with CBT combined with agomelatine.The clinical eficacy,depression degree and suicidal ideation were compared between the two groups.Results The total effective rate of treatment of the observation group was 86.67%,significantly higher than 63.33%of the control group(P<0.05).After treatment,the BDI-21 scores and SIOSS scores of the two groups were significantly lower than those before treatment,and the BDI-21 score and SIOSS score of the observation group were significantly lower than those of the control group(P<0.05).Conclusions CBT combined with agomelatine in the treatment of patients with depression can obviously improve clinical efficacy,reduce the depression degree,and relieve suicidal ideation.