家庭干预对我国精神分裂症患者家庭照顾者焦虑和抑郁状况有效性的meta分析

Effectiveness of Family Intervention on Anxiety and Depression of Family Caregivers of Schizophrenia Patients in China:a Meta-analysis

目的系统评价家庭干预对我国精神分裂症患者家庭照顾者焦虑、抑郁状况的改善效果。方法检索Cochrane Library、PubMed、Web of Science、中国生物医学文献服务系统、万方数据库、中国知网、维普数据库,收集2000年1月—2022年4月发表的关于家庭干预改善我国精神分裂症患者家庭照顾者的焦虑和抑郁状况的文献。共纳入文献11篇,累计研究对象1298例,根据干预方式不同,将患者分为干预组(n=662)和对照组(n=636),干预组采用家庭干预方案,对照组采用常规随访方案。对纳入的文献评价偏倚风险后,采用RevMan 5.4.1软件进行meta分析。结果干预组家庭照顾者的焦虑和抑郁状况较对照组有所改善,差异有统计学意义(P<0.05)。结论家庭干预对我国精神分裂症患者家庭照顾者焦虑和抑郁症状具有改善效果。

Objective To systematically evaluate the improvement of anxiety and depression status of family caregivers of schizophrenia patients in China by family intervention.Methods The literature published from January 2000 to April 2022 on the improvement of anxiety and depression status of family caregivers of schizophrenics in China by family intervention were collected by searching Cochrane Library,PubMed,Web of Science,CBM,WanFang Data,CNKI and VIP databases.A total of 11 articles were included,with a total of 1298 research subjects.According to different intervention methods,patients were divided into an intervention group(n=662)and a control group(n=636).The intervention group was given a family intervention plan,while the control group was given a conventional follow-up plan.After evaluating the risk of bias in the included literature,RevMan 5.4.1 software was used for meta-analysis.Results The anxiety and depression status of family caregivers in the intervention group was improved compared to the control group,with a statistically significant difference(P<0.05).Conclusion Family interventions show an improvement effect on anxiety and depressive symptoms in family caregivers of schizophrenia patients in our country.