摘要
阿尔茨海默病(AD)脑内突触可塑性受损,而目前研究发现,针灸能够通过修复突触可塑性缓解AD认知缺陷。现分别从突触功能和结构、神经递质、突触可塑性相关蛋白及信号通路等角度综述针灸防治AD的机制。
The synaptic plasticity in the brain is damaged in the patients with Alzheimer′s disease(AD).However,studies have reported that acupuncture and moxibustion can alleviate the cognitive deficit of AD by restoring synaptic plasticity.This article reviewed the mechanism of acupuncture and moxibustion in the prevention and treatment of AD from synaptic function and structure,neurotransmitter,and proteins and signaling pathways associated with synaptic plasticity.
作者
林瑶
赵百孝
LIN Yao;ZHAO Baixiao(School of Acupuncture-moxibustion and Tuina,Beijing University of Chinese Medicine,Beijing 100029,China)
出处
《世界中医药》
CAS
2023年第6期877-881,共5页
World Chinese Medicine
基金
国家自然科学基金项目(81574068,81874503)。
关键词
阿尔茨海默病
针刺
艾灸
突触
突触可塑性
Alzheimer′s disease
Acupuncture
Moxibustion
Synapse
Synaptic plasticity
