高尿酸血症肠道尿酸排泄减少相关机制及中药干预研究进展

Research Progress on the Related Mechanism of Decreased Intestinal Uric Acid Excretion in Hyperuricemia and the Intervention of Traditional Chinese Medicine

原发性高尿酸血症(hyperuricemia,HUA)是我国常见的代谢性疾病,目前将血尿酸>420μmol/L定义为HUA。HUA在导致痛风性关节炎、痛风石和尿酸性肾病等并发症的同时,有越来越多的证据表明,HUA还增加了高血压病、糖尿病、血脂异常、慢性肾脏病(chronic kidney disease,CKD)和心血管疾病(cardiovascular disease,CVD)的患病风险[1]。