高频重复经颅磁刺激结合肢体功能训练对缺血性脑卒中患者神经电生理的影响

Effect of high-frequency repetitive transcranial magnetic stimulation combined with limb function training on balance function and neuroelectrophysiology in patients with ischemic stroke

目的探讨高频重复经颅磁刺激结合肢体功能训练对缺血性脑卒中患者神经电生理及平衡功能的影响。方法纳入2021-05—2022-05沧州市人民医院诊治的106例缺血性脑卒中患者,对照组患者采取常规西药治疗和肢体功能训练,观察组患者在对照组的基础上采取高频重复经颅磁刺激结合肢体功能训练,2组各53例,对比治疗前后2组患者的NIHSS评分、Barthel指数、平衡功能(摆幅指数、轨迹长度、外周面积)、神经电生理相关指标[运动诱发电位(MEP)和中枢运动传导时间(CMCT)]。结果治疗后观察组NIHSS评分[(9.25±0.75)分对(11.69±1.12)分]、摆幅指数(4.21±0.45对5.99±0.79)、轨迹长度[(58.62±8.52)cm对(69.77±11.52)cm]、外周面积[(10.05±1.32)mm^(2)对(15.45±2.11)mm^(2)]、CMCT[(7.25±1.12)ms对(8.78±1.69)ms]、MEP[(21.02±1.63)ms对(22.66±2.83)ms]低于对照组,而Barthel指数[(68.11±8.69)分对(60.02±7.02)分]高于对照组(P<0.05)。结论高频重复经颅磁刺激结合肢体功能训练效果更为显著,能更好地改善缺血性脑卒中患者平衡功能及神经电生理。

Objective To investigate the effects of high-frequency repetitive transcranial magnetic stimulation combined with limb function training on balance function and neuroelectrophysiology in patients with ischemic stroke.Methods A total of 106 patients with ischemic stroke treated in Cangzhou People's Hospital from May 2021 to May 2022 were selected as the research objects.According to the random number table method,they were divided into the control group(given conventional western medicine treatment and clinical nursing intervention)and the observation group(given high-frequency repetitive transcranial magnetic stimulation combined with limb function training on the basis of the control group),53 cases in each group.The NIHSS score,Barthel index,balance function(swing index,trajectory length,peripheral area)and neuroelectrophysiological indexes(MEP,CMCT)were compared before and after treatment.Results After treatment,the observation group's NIHSS score((9.25±0.75)scores vs(11.69±1.12)scores),swing index(4.21±0.45 vs 5.99±0.79),track length((58.62±8.52)cm vs(69.77±11.52)cm),peripheral area((10.05±1.32)mm^(2)vs(15.45±2.11)mm^(2)),CMCT((7.25±1.12)ms vs(8.78±1.69)ms)and MEP((21.02±1.63)ms vs(22.66±2.83)ms)were lower than the control group,while the Barthel index((68.11±8.69)scores vs(60.02±7.02)scores)was higher than the control group(P<0.05).Conclusion High-frequency repetitive transcranial magnetic stimulation combined with limb function training has a more significant effect,which can better improve the balance function and neuroelectrophysiology of patients with ischemic stroke.