某院静配中心抗肿瘤药不合理处方分析

Analysis of Irrational Prescription of Anti-tumor Drugs in Pharmacy Intravenous Admixture Services of a Hospital

目的 分析我院静配中心干预的抗肿瘤药不合理处方,并依据不合理类型进行归纳,及时反馈临床,提高抗肿瘤药合理性。方法 统计我院静配中心2021年6月至2022年6月期间审方药师干预的抗肿瘤药不合理处方。结果 共统计出抗肿瘤药不合理用药处方146例,不合理类型有10种,其中配置浓度不适宜是主要因素,占32.87%;溶媒选择不适宜位居第二,占25.34%;预溶溶媒缺失占19.86%。结论 通过统计分析静脉用抗肿瘤药的不合理用药情况,可发现主次要因素,药师可以针对性地进行干预,提高审方水平和效率。

OBJECTIVE To analyze the irrational prescriptions of anti-tumor drugs in pharmacy intravenous admixture services of our hospital,and to summarize them according to the irrational types to provide timely feedback to clinical practice which can improve the rationality of antineoplastic drugs.METHODS Unreasonable prescriptions of anti-tumor drugs,which were intervened by prescription checking pharmacists in the static dispensing center of the hospital from June 2021 to June 2022,were counted.RESULTS A total of 146 cases of irrational prescriptions of anti-tumor drugs were counted.There were 10 types of irrational prescriptions.The unsuitable concentration was the main factor(accounting for 32.87%)while the unsuitable solvent selection ranked the second(accounting for 25.34%).The pre-dissolved medium was missing in 19.86%of cases.CONCLUSION Through the statistical analysis of the irrational use of intravenous anti-tumor drugs,the primary and secondary factors can be found.Pharmacists can make targeted interventions to improve the level and efficiency of prescription review.