我国非酒精性脂肪性肝病的流行病学研究和诊断现状分析

Epidemiological research and diagnosis of nonalcoholic fatty liver disease in China

非酒精性脂肪性肝病(NAFLD)是我国第一大慢性肝病,也是引起健康查体肝功能异常的首要原因。影响NAFLD发病的危险因素众多,不仅包括性别、年龄、代谢综合征等常见的危险因素,还包含睡眠障碍、肌少症等少见但已成为研究热点的因素。近年来,随着饮食结构及生活方式的改变,我国NAFLD的患病率和发病率呈现持续增长和低龄化趋势。流行病学调查有助于NAFLD疾病的诊断、治疗及预防。近年来,国内NAFLD的流行病学资料正在不断完善,本文就近10年来我国NAFLD的患病情况及相关危险因素研究现状进行综述。

Non-alcoholic fatty liver disease(NAFLD)is the most common chronic liver disease in China and the primary cause of abnormal liver function.There are many risk factors affecting NAFLD,including not only common risk factors such as sex,age,metabolic syndrome,but also rare factors such as sleep disorders,myopathia,etc.With the changes in diet and lifestyle,the prevalence and incidence of NAFLD in China are showing a continuous increase and a trend of younger age.Epidemiological investigation is conducive to the diagnosis,treatment and prevention of NAFLD.In recent years,the epidemiological data of NAFLD in China are constantly improved.This article reviews the prevalence of NAFLD and related risk factors in the past 10 years in China.